one in in the front and one out in the back should be more than enough for those parts, none under load will generate any considerable amount of heat, perhaps the gtx and won't reach easily 60°c
be sure to do a decent cable management with the psu cables and check temperatures with hwmonitor or openhardwaremonitor after installing the two fans, you might find that the one in the back for that case makes noise, so perhaps only one in the front or two, but you need to experiment temperatures under load, the one in the back thanks to the shape of the grid proably will make some noise and you will hear it, i think
one recommendation, get another 8 gbs of ram, so you work in dual channel mode, cpu should run better accessing the ram, or 2x4 gbs of ram on dual channel