What is on the USB drive: OS, game, data? I see a setup.exe and autorun files listed.
Make and model USB drive?
Capacity, how full?
I also noted a "reference" to an E: drive - 51% full, NTFS, and possibly 1 TB capacity.
Is that the USB drive in question?
Did you attempt any editing via WinHex? If so, what did you do and why?