sizzling is correct to avoid unpredicted failures you should do clean install on you OS. If you have install Win10 you may have issue because the license is connected to MB SN and for sure you change MB when you change CPU from Intel to AMD. Also if you have newer CPU and your current OS is for example Win7 x.x you may need to install Win10 because there is no support for you new CPU in Win7 (MS stuff). In order to help you we would need version of you old OS, model of you new CPU and MB. If you change the OS from Win7 to Win10 because of your new CPU/MB you the application may not be compatible with new OS too. If you dont have experience with installing/reintalling HW and SW at this level my suggestion is some one who have to do it for you.