I have a Intel 400 series based system a laptop, and if I enable memory core protection then Hybrid Sleep doesn't work in Windows 10. With memory core protection enable "Hypervisor doesn't support this feature". But if disable memory core protection Hybrid sleep enables.
Hybrid sleep is basically hibernate with sleep so that if for some reason you let the battery run dry, you still have hibernate to go off of. Hibernate stores the contents of RAM into the storage drive
Memory Core Protection creates an isolated region in memory to perform system tasks in a more secure environment to mitigate malware attacks. From a security standpoint, it doesn't make sense to copy the contents of the secure environment. Plus it may make it open to attack.