i5 6500 on h110

Solution
No need for a BIOS update. The motherboard should support the Skylake series CPUs (including your i5 6500) right out of the box.

BIOS compatibility becomes a concern on that motherboard when pairing with Kaby Lake CPUs (eg. i5 7500).
No need for a BIOS update. The motherboard should support the Skylake series CPUs (including your i5 6500) right out of the box.

BIOS compatibility becomes a concern on that motherboard when pairing with Kaby Lake CPUs (eg. i5 7500).
 
Solution