Certainly not all liquid coolers are equal....
Little tiny radiators (some 120 mm units) can often be overwhelmed as fluid heats up over time....
Try 4.5-4.6 GHz all core initially, see what your temps lok like prior to worrying about higher clock speeds. (Most people have mid-range GPUs capping their FPS anyway....)
Intel's XTU makes it very easy to jump upward in 100 MHz increments, allowing most things to be altered that would normally be done in BIOS, yet, in the event of instability, everything is set back to defaults making it fairly safe to tinker....