The downsides as I see them on the cheaper boards:
1. If you have very demanding workloads that will put the CPU at 100% load for long periods of time (rendering, encoding, hardcore gaming, benchmarks etc etc) then often the cheaper boards don't have the highest option for power delivery as well as heatsinks on those components. It's more a peace of mind thing for me I think.
2. As mentioned before, some connectors etc are left out, so usually less usb slots, less sata connectors, lower quality onboard sound
3. If you plan on adding additional memory in down the line, try to get an exact match for your current memory. If you can't make sure the timings and speed are the same or as close as possible. Even matching part numbers from different packages of memory can sometimes cause errors which then usually require reducing data rate/loosening memory timings to get them compatible. This isn't a common problem, but CAN occur between same part numbers for memory etc.
Other than those things, which aren't a big deal for you I don't think, I believe you will be perfectly happy with the H81 and 4790 combo. If you are running applications that will fully load the cpu, just make sure to keep some airflow (at least a 120mm intake and/or exhaust fan) in the case and over motherboard components for system longevity.