I agree that the skylake and related chipsets are where I'd go, if building a new system. The z170 is definitely worth stepping up to, if you plan on lots of extras in your system(m.2 pciex4 drives, thunderbolt/usb 3.1, SLI graphics). Something that rarely gets talked about in these kinds of discussions is the heat and power issues.
Only thing to think about, in regards to the OP, is whether he lives in a country where supply of skylake might be difficult to come by.