It is possible , the motherboard mounting screws are followed standard already ,and it is just 4 mounting holes more on the case it self where you mount the heat sink screws.
However this will fix the CPU position on the Motherboard it self .. and I think this is not a bad idea at all , they can choose the best CPU position and make it fixed place , just like the slots places for example..
Here's the problem with that: Is the optimal CPU position the same for TR4 as it is for LGA 1151? Remember, one typically has DIMM slots on both sides of the socket, while the other doesn't. Also, would this "optimal" positioning be the same for every single standardized form factor? I'm guessing no.
In addition, how are you addressing mounting hardware? Are you saying every case should be able to mount everything from sTR4 to LGA 1151 to AM4 to LGA 2011v3? Would you just machine in all of the mounting hardware, increasing the cost of every single case, would you include adapters for every single socket, increasing the cost of the case, or would you just break up the product stack where you can only install one socket type into a case? Hint: None of those are good ideas.
This would also make installation a gigantic pain in the bum. Are you suggesting every single case should have a removable motherboard tray (increasing the cost more) to make installation easy? Or do you have to install the motherboard and CPU, then try to finagle a 2+ kg cooler into the case without busting anything? That sounds worse than the solution we already have.
Lastly, how many people are using 2+ kg tower coolers? Scratch that, how many 2+ kg tower coolers even exist? You're talking about upsetting the entire motherboard/case industry for a tiny fraction of edge use cases. In what world would be completely redesigning your entire product stack to accommodate such a small group of people be financially advantageous?