Without knowing anything else, theres a chance it will.
Generally speaking, RAM is only guaranteed to work in the kits its sold in. Even two identical sticks bought on the same day from the same retailer may not work together.
The more that is different, the less chance of it working.
If you have 2x4 now, and are planning to buy new RAM, it would be best to buy a 2x8GB kit.
Again, even identical sticks may not work together unless they are sold in a kit.
guess ill just swing see if i missAgain, even identical sticks may not work together unless they are sold in a kit.