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Increasing RAM - DDR3 from 4x2GB to 4x4GB

Thanks!
Is there anything in particular I should be looking out for? (e.g. you say low density, I'm not sure where that'd be described).
Like could I pick any desktop DDR3 4x4 kit? (https://www.amazon.com/s/gp/search/ref=sr_nr_p_n_feature_five_bro_3?fst=as%3Aoff&rh=n%3A172282%2Ck%3Addr3+4x4gb+desktop%2Cp_85%3A2470955011%2Cp_n_feature_five_browse-bin%3A677429011&keywords=ddr3+4x4gb+desktop&ie=UTF8&qid=1517165893&rnid=673240011)