Hi there captaincougar,
Keep in mind that initialization is data destructive. So, you don't really want to do that in case you have data stored on the drive.
How is the drive recognized by Disk Management and Device Manager? When you do get that error message about the denied access?
There are quite a lot of threads on missing external drives after Win upgrade. Most of these, are caused by driver related issues.
My suggestion would be to go to your MOBO's website and update your USB drivers.
After that, you can go to Device Manager -> right click on the device and uninstall it -> plug it out -> reboot system -> plug it back in and wait for it to automatically install.
Let us know how this goes,
D_Know_WD