This is a very interesting launch. The W-1290P, which is the 10900K equivalent, is $539, just $40-$51 more expensive (the 10900K MSRP is listed as $488-$499). With just a $40-$50 premium you get ECC memory support, vPro, AMT, EMA, and likely a better binned chip. That at the expense of overclocking but overclocking is not that necessary given that on all locked cpus (including Xeons) you CAN remove power limits and have the CPU turbo boost indefinitely to its stock turbo speeds which are pretty high in this generation anyway. And even on locked cpus and locked motherboards you CAN change the BCLK to 102-103MHZ so 49x102 or 103MHz and you reach or exceed 5GHz. As for RAM, if you are buying this over the 10900K it is because of ECC and there is no ECC UDIMM that is clocked over 3200MHz anyway. And 2933MHz with lower timings is just as good plus we are talking about a 0-2% difference to begin with even with looser timings. Also W480 boards, much like the former C646 boards, are cheaper, and in many ways more feature-rich, than their Z490 counterparts that are overengineered to handle extreme 7GHz+ overclocks that nobody can attain due to cooling limitations.
Here is a workstation build that I would personally be contemplating for a total of $2750: CPU: Intel Xeon W-1290P (10C/20T 5.3GHz/4.9GHz) - $540 - here M/B: ASUS Pro WS W480-ACE - $295 - here RAM: 64GB (2x32GB) ECC UDIMM - DDR4-3200 (run at 2933 with lower timings) - Nemix ME25600-328K02-G (SK Hynix chips) - $460 Storage Drive: 2TB Adata XPG SX8200 Pro - M.2 NVMe - $260 - here GPU: Nvidia RTX Ampere based xx80 series (2080Ti equivalent) - $720 CPU Cooler: Noctua NH D15 Chromax Black - $90 -here Case: Fractal Design Define 7 - $160 - here Power Supply: Corsair HX850i 850W 80 Plus PLATINUM - $225 - here