Unless you think that AMD is going to give more cores for the same price it certainly is still true as dense core CCDs only come in 16 core configurations. 16 full cores are always going to be faster than 16 dense cores are unless you're starving them for power which client configurations do not. I don't see AMD changing up to lower the core count on dense CCDs as they have definitely minimized the amount of CCD configurations they make.
All fully enabled configurations need to limit power, Clients and EPYCs alike, just typically at a somewhat higher amount of total Watts.
My 16 core Ryzens (5000 and 7000) do double digit Wattage per core at lower core counts, but once they're lighting nearly all up, they'll have no choice but to drop to lower frequencies and typically to below 10 Watts/core. And that opens a windows or opportunity for compact cores because at the remaining Wattage per core, frequencies on L cores is nearing their max clocks.
It's a somewhat similiar situation with the mix of V-cache and non-V-cache CCDs on my 7950X3D, which doesn't really suffer from its VC imposed max clock/Watt limitations, when they light up as cores 9-16 and everybody already has to do with less than 10 Watts.
A hypothetical 4L/8C CCD might be able to make do with the same surface area as 8L or 16C variants and thus two could fit into the surface constraints on the AM4/5 sockets. No idea if the client IOD could manage such a mix, but both the 4L/8C and the 16C CCD variants could have their niche on µ-servers/workstations or "client" devices, deven if AMD may also not be that hot on diluting a "server market" with such economy hardware.
In terms of production cost I guess 8L, 4L/8C and 16C CCDs would be nearly equal since that is mostly die size driven, apart from the fact that evidently the hybrid CCD would be an extra SKU (since it's not an APU). But once they have the production scale, that might not even be an issue.
Another intersting academic debate would be if dual 4L/8C or a mix of 8L and 16C CCDs are better for performance, while the latter saves AMD the extra CCD variant.
I'm not saying it's very likely AMD would do that, unless Intel somehow makes 24 cores appear extremely sexy.
I'm mostly saying they are in a pretty good position to be able to do that, should the need or opportunity arise.