I have been researching this in connection with a Canon DR-3080C, and the question is whether the scanner will be recognized, since the software doesn't know to look for it on a usb port. One of the posts I read elsewhere mentioned that this was a problem when they tried a usb cable to get away from using a scsi host card (unfortunately, I can't remember the exact location of the post - I have been doing a LOT of research these past few days).