The electrical tape would work, but you would be insulating it, not grounding it.
Grounding power literally means causing it to flow into the ground as in planet Earth.
The ground as in the dirt outside is a conductor of electricity.
By having a connection to it, you can help ensure that there is not a catastrophic buildup of power in a piece of equipment.
The electrical tape would sit between two pieces of metal and impede current passing between the two not unlike when plastic sleeves are on wires in order to prevent the metal in one wire touching the metal in the other wire therefore preventing a short circuit.
Anyway, you have the right idea. By using electrical tape or something like it you can impede the flow of electricity from the motherboard to a separator.
I would, however, just hack off the separator if it were me, because even with electrical tape it could potentially cause the board to bend around it which could potentially have drawbacks. If you just hacked it off then the motherboard would not be forced to bend at that point to compensate for the separator pushing on it.