The R5 -
http://www.fractal-design.com/home/product/cases/define-series/define-r5-black
comes with -
Front: 2 – 120/140 mm fans (included is 1 Fractal Design Dynamic GP14 fan, 1000 RPM speed)
Rear: 1 – 120/140 mm fan (included is 1 Fractal Design Dynamic GP14 fan, 1000 RPM speed)
Top: 3 - 120/140 mm fan (not included)
Bottom: 2 – 120/140 mm fan (not included)
Side: 1 – 120/140 mm fan (not included)
1 front and 1 rear.
I'd start with just what is supplied - which should be adequate for most builds. If needed, I'd add another one to the front and top.