[SOLVED] Is it advisable to change download location away from OS SSD drive..?

Solution
Moving files to other drives will not protect from viruses or other malware. If the drives are connected to an infected system they will be just as infected as the system drive.
Nov 20, 2018
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But including all you guys mentioned, isn't it recommended to change download location from main SSD with OS installed in it to other less important HDD in order to protect against drive corruption from virus?

or I'm mistaken and it's completely irrelevant?