One thing you could look into, which I personally like to do when using fast RAM, is to manually lower IO and SA voltage. I've had two different Z390 motherboards with my 9900K CPU and 3600MHz RAM, and both motherboards set an unneccessarily high IO and SA voltage. Not dangerously high or anything (1.3 -1.35-ish volt), but my CPU and RAM runs fine with a lower 1.10V IO and 1.15V SA voltage - and anytime I can lower voltages slightly, I prefer to do so - as an added benfit, it did shave off a couple of degrees 'C from CPU max temp.
I know you are looking into 10th Gen, and mine is a 9th Gen, so they might not behave the same. But it is something you could consider looking into, although not really neccessary