My CPU cooler is an Asus - ROG RYUJIN 360 121.8 CFM Liquid CPU Cooler
My RAM is G.Skill - Aegis 16 GB (2 x 8 GB) DDR4-3000 Memory
My RAM is G.Skill - Aegis 16 GB (2 x 8 GB) DDR4-3000 Memory
https://pcpartpicker.com/product/3MJkcf/asus-prime-z370-a-atx-lga1151-motherboard-prime-z370-aNo, why would it? It's a water cooler, not an air cooler. It shouldn't come anywhere near the closest DIMM slot. What motherboard do you have?