Is there any issues with this build?

[AviIsAHuman]

So I put together this, is there any issues with it? Will they all fit and not implode. What are some tips before I go ahead and build it.

http://pcpartpicker.com/list/qxtqm8

 

[sadams04]

A few things...

MB - A benefit to the Z170 chipset is the ability to run multiple GPUs. The Gigabyte Gaming 5 is a good board, but that one is a micro form factor. Best to stick with a full sized ATX board for its expansion options.
MEM - Z170 is fine above DDR4-2133, but try to stay at 1.2v. You should be able to find good DDR4-2666 or DDR4-2800 modules for less cost than those expensive Kingston standard spec modules.
SSD - Add one now. You won't regret it...
PSU - Up that size to 850w if you want to keep the option open to add a second GTX 1080 down the road.
WIRELESS - Changed to an AC model.
CASE + FANS - A cheaper option is below.

PCPartPicker part list / Price breakdown by merchant

CPU: Intel Core i5-6600K 3.5GHz Quad-Core Processor ($227.99 @ SuperBiiz)
CPU Cooler: Cooler Master Hyper 212 EVO 82.9 CFM Sleeve Bearing CPU Cooler ($29.99 @ Newegg)
Motherboard: Asus Z170-E ATX LGA1151 Motherboard ($127.99 @ SuperBiiz)
Memory: G.Skill Ripjaws 4 Series 16GB (2 x 8GB) DDR4-2666 Memory ($68.99 @ Newegg)
Storage: Sandisk Z400s 256GB 2.5" Solid State Drive ($69.99 @ Newegg)
Storage: Western Digital Caviar Blue 1TB 3.5" 7200RPM Internal Hard Drive ($47.49 @ OutletPC)
Video Card: Asus GeForce GTX 1080 8GB STRIX Video Card ($739.50 @ B&H)
Case: Fractal Design Define S w/Window ATX Mid Tower Case ($79.99 @ SuperBiiz)
Power Supply: EVGA 850W 80+ Gold Certified Fully-Modular ATX Power Supply ($128.99 @ SuperBiiz)
Operating System: Microsoft Windows 10 Home OEM 64-bit ($92.99 @ Best Buy)
Wireless Network Adapter: Gigabyte GC-WB867D-I PCI-Express x1 802.11a/b/g/n/ac Wi-Fi Adapter ($29.89 @ OutletPC)
Case Fan: Fractal Design SSR3-140-WT 56.1 CFM 140mm Fan ($7.49 @ SuperBiiz)
Case Fan: Fractal Design SSR3-140-WT 56.1 CFM 140mm Fan ($7.49 @ SuperBiiz)
Total: $1658.78

 

[AviIsAHuman]

A few things...

MB - A benefit to the Z170 chipset is the ability to run multiple GPUs. The Gigabyte Gaming 5 is a good board, but that one is a micro form factor. Best to stick with a full sized ATX board for its expansion options.
MEM - Z170 is fine above DDR4-2133, but try to stay at 1.2v. You should be able to find good DDR4-2666 or DDR4-2800 modules for less cost than those expensive Kingston standard spec modules.
SSD - Add one now. You won't regret it...
PSU - Up that size to 850w if you want to keep the option open to add a second GTX 1080 down the road.
WIRELESS - Changed to an AC model.
CASE + FANS - A cheaper option is below.

PCPartPicker part list / Price breakdown by merchant

CPU: Intel Core i5-6600K 3.5GHz Quad-Core Processor ($227.99 @ SuperBiiz)
CPU Cooler: Cooler Master Hyper 212 EVO 82.9 CFM Sleeve Bearing CPU Cooler ($29.99 @ Newegg)
Motherboard: Asus Z170-E ATX LGA1151 Motherboard ($127.99 @ SuperBiiz)
Memory: G.Skill Ripjaws 4 Series 16GB (2 x 8GB) DDR4-2666 Memory ($68.99 @ Newegg)
Storage: Sandisk Z400s 256GB 2.5" Solid State Drive ($69.99 @ Newegg)
Storage: Western Digital Caviar Blue 1TB 3.5" 7200RPM Internal Hard Drive ($47.49 @ OutletPC)
Video Card: Asus GeForce GTX 1080 8GB STRIX Video Card ($739.50 @ B&H)
Case: Fractal Design Define S w/Window ATX Mid Tower Case ($79.99 @ SuperBiiz)
Power Supply: EVGA 850W 80+ Gold Certified Fully-Modular ATX Power Supply ($128.99 @ SuperBiiz)
Operating System: Microsoft Windows 10 Home OEM 64-bit ($92.99 @ Best Buy)
Wireless Network Adapter: Gigabyte GC-WB867D-I PCI-Express x1 802.11a/b/g/n/ac Wi-Fi Adapter ($29.89 @ OutletPC)
Case Fan: Fractal Design SSR3-140-WT 56.1 CFM 140mm Fan ($7.49 @ SuperBiiz)
Case Fan: Fractal Design SSR3-140-WT 56.1 CFM 140mm Fan ($7.49 @ SuperBiiz)
Total: $1658.78

Hell yeah that looks amazing! Thanks so much