If you want to believe that level of performance is good enough for you, more power to ya. The bottleneck is severe, but there will be no hardware damage, the GPU will probably actually run cooler because it is idling more. The FX4300 is arguably on par with a core 2 duo Q9650. And back in 2011, I already detected that the Q9650 bottlenecking the GTX560ti. The 1050ti is almost 2x faster than the 560ti, so the bottleneck will be even worse.