Is this compatible?

Yes, I has 1 PCI x16 slot for a graphics card. So yeah any GPU will work with this :)

Be careful of the case size and the actual card! But I HIGHLY recommend another motherboard. Even a small Gigabyte or ASUS board. If you could post as much specs as you can I could try and find a small and cheap motherboard that would work a lot more efficiently. Than that board.