It safe to overclock a sapphire r9 280x toxic?

Lunix89

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i've been thinking about further overclocking my card a bit, which is already overclocked quite a lot. i've download sapphire trixx to do so. what kind of levels would be safe to oc at? i cant find any video guides for overclocking this card, nor any other discussions about it.
 

Lunix89

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wont that burn the card out?

my setup is;

i5 4670k
corsair h100i
msi mpower max
xfx 850w black edition
sapphire r9 280x toxic

so i have a good cooler and psu, but not sure what would be pushing it too far.

which is better out of msi afterburner or sapphire trixx?
 

Lunix89

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for some reason, when i over clocked my card like you said, when i open diablo 3 it just goes to a black screen and i can't do anything. can't minimize, do ctrl alt delete or anything and i just have to turn the pc off.