JUSB3 and JUSB4?

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Jul 6, 2017
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Motherboard: MSI Z270 A PRO (https://pcpartpicker.com/product/KvvZxr/msi-z270-a-pro-atx-lga1151-motherboard-z270-a-pro)

Hi, I'm building my first PC, and on my motherboard, there are two places to connect my USB 3.0 case headers: JUSB3 and JUSB4. My motherboard's manual only tells me that those two are used for USB 3.0 case headers. Does it matter which place I connect my USB 3.0 headers?

The reason I ask this is because I fear my video card will block the JUSB3 connection, so I may have to use JUSB4.