1 x M.2 x4 Socket 3, 2, with M Key, type 2242/2260/2280/22110 storage devices support (both SATA & PCIE mode)3
so yes any M.2 SSD with M key would work
6 x SATA 6Gb/s port(s), gray
So 6 places to plug any SATA HDDs to except one will be disabled in case of using M.2 port but you have 5 more left.