Hey there, DarkDestinny.
From what I was able to find out about the mobo's specs, it seems like you'd have to stick with 2TB drives. Here's the thread to prove it: https://forum-en.msi.com/index.php?topic=164678.0. Otherwise @WyomingKnott's advice is spot on about initializing larger than 2TB drives.
Hope that helps.
Boogieman_WD