I did something like this back in the early 2000's.
I worked for a company that used Octo-media USB card readers, (8 cards read by one USB device) and had plugged a lot of them into my machine, probably about 8 or more to think of it.
My PC worked fine, but was very unstable.
i was testing the devices out, to be able to see if they were fixed (bent pins in the SD card slot).
My PC would often reboot, and I got the BlueScreen code, and checked it, and it was due to overloading the USB power supply.
A powered USB hub solved the problem, but i used a dedicated PC from then on, rather than my work PC...