Mouse input stops

[Temreguy]

Win 10: Microsoft usb mouse (3 yrs old) doesn't register clicks on links. All fine until 2 weeks ago. Have to Restart to fix. Ideas?

 

[Lutfij]

Go through this tutorial:
Keyboard and mouse stop working when windows 10 boots up fix.

Furthermore, even if its a three year old mouse, I'm sure it will register on Microsoft's Mouse & Keyboard Center and essentially suffice as the driver and third party manager for your pointing device.