Necroing again as the problem persists but I have some new, hopefully helpful info. I started using a wired mouse( same brand ) and noticed it was disconnecting and reconnecting when the problem was happening, I only know this because of the beeps it was making, however the wireless mice made no such beeps. Also I have an xbox controller hooked up that never has a problem, I also have a pen and tablet that never has a problem( i.e. no severe cursor lag, etc with either ). I went and bought a new mouse( new brand and drivers and all ) but the problem is still here. I read that on windows 10 an update for the xbox controller was causing similar issues, but I'm on windows 7, but decided to uninstall the xbox controller drivers regardless and there is no change. Any help or theories would greatly be appreciated.