Would be good to know where the source of the noise and vibration are each coming from. Are they both the same, or are they separate issues?
We will need more feedback in order to have a better idea.
To note - standard hard drives will vibrate a bit while operational, they have rotating mass inside, so while they are very balanced, there is still a slight vibration as they spin. If this is very noticeable or noisy from the drive itself, that is reason for concern.
This also could be a loose fan, wire hitting fan blades, a mount which is a bit loose and vibrating...many things. We need more detail.