Anytime
Ok if you are not getting any response at all that suggests a power issue or something else on the more serious end of things. If it were a drive issue i would expect it to at least post and then crash. An in depth process of elimination would require you to have spare hardware to test in. The most pressing concern is a potentially bad power supply as that could cause damage if left as it is. If you have a spare PSU i would try that first but if not then the best course of action would likely be to find a computer repair shop near you and have them test it to see if that is at fault.