You could try and replace the audio cable used to pair the speakers to the sound card and see if that alleviates the issue. You can also try and make sure you're sound card is up to date with the latest drivers and that the motherboard's BIOS is up to date. On second thougths, please list your specs like so:
CPU:
Motherboard:
Ram:
SSD/HDD:
GPU:
PSU:
Chassis:
OS: