I got a Zotac 1050ti mini and tried to run it with my old Quadro k600 so i could use the k600 for my other non gaming monitor. My motherboard burnt out when i tried to start it. No fans or anything came on. I bought the same motherboard again and the 1050ti works fine on it. I am scared to try to use the k600 in the PCIE 4x slot because I don't want to buy another motherboard if it burns out. Is this a coincidentally weak motherboard or was it due to the GPUs?