Well, there are some issues:
1) From what I can tell, none of the motherboards that use that CPU use DDR3 RAM, they all use DDR4 RAM. So you will have to buy RAM to go with it.
2) I've been having trouble tracking down dual-socket motherboards for the LGA 2066 chips. It looks like they're gearing the dual-socket platforms for the Xeon W chips (https://wccftech.com/intel-xeon-w-workstation-cpu-family-launched-c422-lga-2066-platform/, https://www.anandtech.com/show/11775/intel-launches-xeon-w-cpus-for-workstations), which use a different chipset (C422) than that used by the Skylake-X chips (X299)...& it kind of looks like the Xeons won't work in a X299 motherboard, so I don't think the Skylake-X chips will work in a C422.
3) Price-wise, you'd be paying a lot of money for a 4C/4T CPU. With that particular CPU you chose, you're looking at about $420 USD just for the CPU & motherboard (https://pcpartpicker.com/list/kNTF6X)...& you still need to buy DDR4 RAM & a CPU cooler. You could save yourself about $55 USD by going for a Coffee Lake i5-8600K & a motherboard (https://pcpartpicker.com/list/pZyX4C) -- enough to cover the cost of the CPU cooler -- & you'd get a 6C/6T CPU to boot.
EDIT 4) Final note: GTX 1060 (3 or 6GB model) cannot be SLI'd with a 2nd GTX 1060. You need at least a GTX 1070 or better for SLI to work.