would the performance increase justify the nearly $300 to upgrade from my current 3200mhz CL16 32gb kit.
Another note about my current kit, I have 2 8gb sticks from samsung and the other 2 sticks from micron. I was informed this is not a good thing and should change my kit immediately. Again, I'm not sure if all this information is accurate or not.
Ideally.....you want all 4 sticks to be part of a single package, purchased in a packet of all 4 at the same time. Usually referred to as a "kit". That's to avoid issues and get the best possible performance. Any other way can "work", but it's a risk.
You say "justify"................quite a word.
If your net worth is 50 million dollars, most likely yes.
If your net worth is 50 thousand dollars, maybe.
If your net worth is 500 dollars........highly unlikely.
But if you are obsessed with the last possible tenth of a percent of performance, maybe you spend your last dollar on different RAM.
If you are expecting anywhere near a night and day difference, you will be disappointed............but for all anyone knows you will be highly satisfied with even the slightest improvement.
Pretty much your call depending on where you fall on that continuum.
If the new RAM costs 200 bucks, maybe 200 spent elsewhere would be a lot more bang for the buck.