Update your post to include full system hardware specs and OS information.
Refer to the applicable (GPU and Motherboard) User Guide/Manual's to learn what the orange LED's may be indicating.
Regarding "next to usb ports" - you must identify the specific port associated with the LED. There should be some icon identifying the port type.
Likely some multiple meaning either via color, flashing, or both. Look for flashing patterns and/or speeds.
Flashing orange on top might be disk activity via some case connection - check the case documentation as well.