Good, you should be able to POST with all 4 sticks of RAM.
It's probably not dangerous to increase the voltage with only 2 sticks; but you don't want to increase to the point you fry the RAM. You only want to raise the voltage enough to POST and achieve RAM stability.
With all 4 RAM sticks in the slots, I would incease the voltage +.1, save and exit BIOS, and reboot. I would continue doing that in +.1v increments until the computer posts.
Your RAM datasheet shows the RAM should run at 2.6v +/-.1v, if cannot get it running stable at 3.0v, I think I would stop trying.
So, you've incrementaly increased the voltage and you POST, now you want to boot into
memtest86+ (latest version) to test the RAM for errors. Use the precompiled executables on your floppy, cd, or usb stck to boot from POST to memtest86+, see the linked page. If you get errors, you can again incrementally increase the RAM voltage, each time booting into memtest to check the RAM for errors. Stop when your RAM runs error-free, or you think the voltage is too high.
I usually do the memtest86+ on each stick individually, in each slot, before I run it on the final configuration so I know each stick and slot is good. You might be able to skip that since you have had 2 goods running for a while.