Question New system powers up, no signal to monitor, then turns off after less than a minute?

Second PCIe slot, yes. But same thing happens with or without the video card

Ok do this. Take that system and put it on a box. Not on metal.

Remove 3 of your RAM sticks and leave only 1 stick in the appropriate slot from your manual when using only 1 stick. Put that GPU in the first PCIe Slot.

Just want to add that the BIOS version of this motherboard needs to be at least 7B22v24 for that CPU to be supported. If your board is not at that version this CPU cannot be booted.