What's the audio card chip ? Is it a offboard card or motherboard onboard like RealTek or anything? If so try reinstalling the Audio driver, also what's your full specs (CPU, RAM, GPU, PSU, OS) ? Where's the sound being reproduced at? Speakers ? TV?
If you have more than 2 sound output devices, you should go to Windows Control Panel / Sound Settings and set only one as the "Default Playback Device".