Sometimes if you are running something at too high of settings for a particular game (like a heavily modded Skyrim for example) you get a crash when either your RAM usage exceeds 4GB (due to the 32bit cap) or your VRAM exceeds your cards limits (2GB).
If you get a error specifically saying "low *video* memory" it is probably your GPU simply is bumping against the max it can do, then something pushes it over and the game crashes to save the card from possible damage (or lockup). This tends to happen when you've modded the game heavily, the game is poorly optimized and "leaks" over time, or you have the settings higher than the VRAM can handle (some games like GTA V require over 4GB of VRAM for higher settings now).
I'm afraid the only real solution is to either turn the settings down to eliminate (or delay) the crash, or upgrade to a new card with 4-6GB of VRAM. (VRAM and RAM are separate items, the VRAM is attached directly to your card, the RAM won't affect "video" memory unless its DDR4). There is a possibility there are stability patches out there that would let you run closer to that 2GB ceiling more stability, but there is no guarantee. I suppose the final question is: what game is crashing? Since some games crash *alot* lol.