There is no visible differences between "12VHPWR" and "12V-2x6", you can use them interchangeably. Manufacturers have just rebranded the products, several without changes. "12VHPWR" is defined by specifications CEM 5.0 and "12V-2x6" by CEM 5.1. The commercial rebranding was just to reassure users.
CEM 5.1 address two causes or errors from the twelve causes of melting analyzed on CEM 5.0, it was the two main causes, it's means that ten causes of melting remains on CEM 5.1.
CEM 5.1 complete the specifications by example in adding on tolerances and alloys, trying to set a minimum in the product quality. It's remains up to manufacturers to ensure the products are up to specifications and safe (they are holes in the specifications remaining to ensure a minimum of surface of contact).
Every month they are several cards or connectors stampeded 12VHPWR melting because of defective connectors that should have not been passed by control of quality. The main culprit for those cases
are the square pins which are difficults to produce with accuracy.