Michael Mansour :
I have an amd phenom x4 975 3.6 GHz 10 gigs of ddr3 ram and an ASUS M4N75TD mobo at a resolution of 1600 x 1200
You have a very decent gaming rig, so the 650ti will run well. But because of it's limitations you won't see massive FPS in games. Still will be med-high with decent frames, and will be smooth enough gaming, with maybe having to dial back AA and AF so not to take too big a performance hit.