NVME M.2 on x99 chipset

[bem602]

I'm saving for a dream PC and like the idea of a M.2 on PCIE x 4 running NVME. The motherboard I want is the Asus x99 A. I've looked and looked for anything saying that it's NVME compatible with a M.2 as boot drive. I can't find it. However, I built a computer for a friend using the Asus x99 a and there is a setting in the BIOS for NVME. I did not have an M.2 drive to play with it so my question is this: Would the X99 A run a M.2 boot drive over PCIE without the issues that come with using it on anything but z170?

 

[TbsToy]

Works just fine. Mine has been running flawlessly that way since last June. X99 A/USB3.1 and an Intel 750 SSD PCI-e.
W.P.