Scrap OC G II and use MSI Afterburner for OC'ing your GPU... OC G II, has issues with:
1- Maintaining OC profiles
2- Maintaining manual fan profiles
3- Maintaining power-target settings (as you are currently encountering)
It looks pretty, but is not a viable/reliable OC utility. This is speaking from personal experience AND Tom's is full of postings with OC G II having issues.
Just some friendly advice given on this and MSI AB is very easy to use by the way...
If you want to have the ability to change and update your LED on your GPU while using MSI AB (or any other OC utility for that matter), here's some steps I created as a work-around:
http://www.tomshardware.com/answers/id-2727719/gigabyte-980-guru-work.html
Scroll down, until you see "BEST SOLUTION", for the LED issue.