ALWAYS INCREASE IN SMALL AMOUNT TO BE SAFE ESPECALLY IF YOUR NEW TO THIS!
it may be alright to do in one big shot but i never would better be safe than sorry!
asso it only take a tiny little while longer anyway to increase slowly!
If you are trying to find your fsb ceiling, drop your multiplier down to the lowest and work on your fsb - leaving most things to auto and ram to 1:1... that will get your started.