Tom1996 :
Main C drive: 381GB
Program files(x86) 227GB
Users: 47GB
Program files: 30GB
Amd: 27.5GB
Windows 23GB
<files> 15GB
Program data: 11GB
Which of these can i move to the spare HDD?
As a whole folder, none of them.
They all have ties to the operating system.
There is no one part of that drive that you can call "the OS" and move everything else.
Your "Program Files" of 227GB. What's in there? Games, I presume?
Your Users folder of 47GB. Find your personal files in there and move those. Not the whole folder(s), just the actual files.
But from what I'm seeing, you're going to have to remove almost
everything, to get to a size where you cn clone it.
And if that is the case, you might as well just do a clean install on this 120GB SSD and start over.
You have too much stuff, and too small a drive.