Sorry, another silly question: are they plugged in and turned on?
Good.
Re-boot, open the BIOS and make certain that the on-board sound is chosen. Sorry, I don't recall what the UEFI bios calls it but it should list something about RealTek. Remember that Realtek also runs your LAN/Ethernet, and we don't want to mess with that.
JUst a thought here:
Unplug the HDMI cable from the monitor, unless it is how you are getting your picture/video.
(If this is how you hooked your video card to your monitor it may be the only way to get sound until you unplug it and run a DVI or Display port cable to the monitor)
If you haven't already done it, open the Control Panel, click on and open 'Sound', if your speakers show up (they will be listed as "Speaker" Realtek High Definition Audio), make certain they are check marked as the Default Device. UN-check any HDMI output that is checked.
Rt. click your speakers (still in 'Sound'), click properties, open the Advanced tab, and make sure the boxes under "Exclusive Mode" are unchecked. Click o.k., that will return you to the main sound window, click the 'sounds' tab at the top, choose a sound,
such as Asterik, and test it at the bottom of the window. Hopefully you will have sound.
It's late here in the West, and I have had it for the day. Sorry if you have done all of these things, but you have given us limited info. If you have tried all these, or you do try them, post back please and I will try to help tomorrow. Good night, 'chat' with you tomorrow.