Taken from the Memory FAQ Sticky:
DUAL CHANNEL
Q: What is Dual channel?
A: See key term: dual-channel.
Q: I currently have two sticks of 512mb pc3200 memory in DIMM 1 and 3 to reach the performance of dual channel DDR. Can I also add two sticks of 256mb PC3200 in dimm's 2 and 4 to reach 1.5GB of ram and still maintain dual channel performance?
A: As long as you have matched memory pairs on each channel, you should be able to run dual channel.
The only potential problem: Because you are using 4 memory modules, which require more power, your system may clock the speed of the modules down to maintain stability.
Q: How do I know if dual-channel is working in my system?
A: An easy way to tell is to use CPU-Z (from www.cpuid.com). You can check if dual-channel is enabled by looking at the memory tab. In the General section, you will see a field labeled as ‘channels #’ which will indicate if dual-channel is working.
Q: Can I add 256MB and 512MB modules together?
A: Yes. Make sure you do not exceed the total memory size.
Q: Do I have to install memory in pairs?
A: It depends on your motherboard. Consult with your motherboard’s manual to see how dual-channel works on your board. For most dual-channel boards the memory modules must be identically sized, and have the same number and type of chips. Typically, the motherboard requires the modules to be inserted in pairs on either slot0 and slot1, or slot2 and slot3. For some other motherboards three modules can run in dual-channel (the numbers of chips, not the modules themselves, are divided between the two channels). In any case, it is best to match the latency and speed of the modules, though it is not required.
Or, read this article, it even has a picture of a Dual Channel setup on the 2nd page and some benchmarks on performance.
http://www.devhardware.com/c/a/Memory/Dual-Channel/1/