The general rule of thumb is a high quality 500 to 550 watt power supply with sufficient current (amps) on the +12 volt rail(s) can easily power a system with any single video card made. A high quality 700 to 750 watt power supply with sufficient current (amps) on the +12 volt rail(s) can power a system with two video cards operating in dual mode. There are a few exceptions like the new ATI Radeon HD 5XXX series cards which use less power due to their energy efficiency.

A high quality 500 to 550 watt psu will have a +12 volt rail rated at 40 amps. A high quality 700 to 750 watt psu will have a +12 volt rail rated at 60 amps.

In addition the power supply should be at least 80+ Bronze certified for energy efficiency. There are some models available which have achieved 80+ Silver and 80+ Gold Certifications.